A recent case report describes the treatment of primary Sjögren's syndrome complicated by immune thrombocytopenia using tofacitinib.
Sjögren's syndrome is an autoimmune disorder mainly affecting the salivary and lacrimal glands, which produce saliva and tears.
The addition of immune thrombocytopenia, characterized by low platelet counts due to immune dysfunction, complicates disease management.
Tofacitinib, an immune-modulating medication, was used to address the autoimmune components of both conditions.
This treatment approach reflects ongoing efforts to find effective therapies for complex autoimmune diseases like Sjögren's syndrome, which can have systemic complications including lymphoma and neurological issues (Ning et al., 2025).
Clinical Trials
This is a list of upcoming or ongoing clinical trials that are actively recruiting and have been listed or updated in the last two weeks:
