Sjögren's Syndrome Insights

This week's must-know community updates, latest research & events

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Top Stories

Latest Research

In a recent study published by the Journal of Inflammation Research (2025), researchers have highlighted the complex role of Salivary Gland Epithelial Cells (SGEC) in Sjögren's disease. SGECs are not only victims of autoimmune injury but also play a significant role in saliva secretion. The study delves into how these cells can both protect against and contribute to the disease's progression. It emphasizes the importance of understanding the balance of calcium, endoplasmic reticulum, and mitochondrial homeostasis in SGECs, as well as the impact of Pattern Recognition Receptors and programmed cell death on these cells.

The findings suggest that targeting SGECs could be a promising approach to treating Sjögren's disease by addressing the inflammatory response in the salivary glands. This underscores the need for further research to fully understand the dual role of SGECs and develop effective treatments that can restore salivary gland function and improve patients' quality of life.

Community News

Sjögren's FoundationSjögren's FoundationMar 03, 2025

According to our 2021 Living with Sjögren's Patient Survey 82% of Sjögren's patients experience joint pain and 72% of Sjögren’s patients experience muscle pain.

Sjögren's Foundation Post
Sjögren's FoundationSjögren's FoundationMar 04, 2025

#TipTuesday: When preparing for surgery, provide your physician with a final list of medications you will bring to the hospital. Ask your doctor if an order can be included on your chart stating that you may take these medications on your own.

We encourage you to share this tip on your page and comment below with your experience(s).

Sjögren's Foundation Post
Beyond Sjögren'sBeyond Sjögren'sFeb 27, 2025

Although hair loss is not a direct symptom of Sjögren’s, it can be a side effect of the condition and its complications, and many people with Sjögren’s can experience hair thinning or increased shedding due to underlying factors linked to the disease, let's explore what they are.

➡️ Several factors can lead to hair loss in Sjögren's, including:

- Thyroid dysfunction & hormonal imbalances, which can often overlap with Sjögren's.

- Chronic inflammation disrupting the hair growth cycle, leading to increased shedding.

- Nutrient deficiencies, including Vitamin D, B, omega 3s and others which are essential for hair health.

- Reduced oil production, which can lead to a dry, irritated scalp and brittle hair.

- Some medications used for Sjögren’s, which can list hair loss as a side effect.

- Chronic stress, which can disrupt the hair growth cycle.

➡️ How can you promote healthy hair growth?

1️⃣ Do regular scalp massages, as studies show they can help increase hair thickness and reduce hair thinning.

2️⃣ Use gentle, sulfate-free shampoos and light oils like argan or jojoba to protect hair strands.

3️⃣ Do your best to manage stress, as chronic stress impacts hormone balance and increases inflammation.

4️⃣ Try your best to follow a whole foods anti-inflammatory diet, which will help address deficiencies and reduce inflammation.

5️⃣ If hair loss persists, consider getting tested for other potential dysfunctions that could be impacting hair loss (such as thyroid dysfunction).

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